Antidote List 2008

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Illinois Poison Center Antidote List Uses and Suggested Minimum Stock Quantities for Various Poison Antidotes Used for Treatment of Poisonings Illinois Poison Center 24-hour Hot line: 1-800-222-1222

 Ant id ot e Sodium bicarbonate

Pois on /Drug /Toxi n Chlorine gas Hyperkalemia Serum Alkalinization:  Agents producing a quinidine-like effec effectt as noted by widened widened QRS complex on EKG (e.g., amantadine, carbamazepine, chloroquine, cocaine, diphenhydramine, flecainide, propafenone, propoxyphene, tricyclic antidepressants, quinidine and related agents) Urine Alkalinization: Weakly acidic agents (e.g., chlorophenoxy herbicides, chlorpropamide, methotrexate, phenobarbital and salicylates)

Sugg est ed Min im um St oc k Quan ti ty Twenty 50 mEq vials

Ratio nal e/Comm ent s Stock 10 vials in the ED and 10 vials elsewhere in the hospital.

®

Succimer (Chemet )

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 Arsenic Lead Lewisite Mercury

One bottle of 100 capsules (100 mg/capsule)

Stock in pharmacy. FDA approved only for pediatric lead poisoning, however it has shown efficacy for other heavy metal poisonings.

2008 Illinois Poison Center

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Illinois Poison Center Antidote List Uses and Suggested Minimum Stock Quantities for Various Adjunctive Agents Used for Treatment of Poisonings Illinois Poison Center 24-hour Hot line: 1-800-222-1222   10 mg/2 mL.

days. Diazepam is also used in poisoned and nonpoisoned patients as an anticonvulsant, muscle relaxant, and antianxienty antianxienty agent. Note: Benzodiazepines are a mainstay in the treatment of NMS and serotonin serotonin syndrome. Adequate supply is necessary to be prepared for weapons of mass destruction (WMD) incidents. Auto-injectors are available from Bound Tree Medical, Inc.

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Illinois Poison Center Antidote List Uses and Suggested Minimum Stock Quantities for Various Adjunctive Agents Used for Treatment of Poisonings Illinois Poison Center 24-hour Hot line: 1-800-222-1222  

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2008 Illinois Poison Center

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Illinois Poison Center Antidote List Uses and Suggested Minimum Stock Quantities for Agents Used for Radiological Exposures Illinois Poison Center 24-hour Hot line: 1-800-222-1222  

 Agen t Calcium-diethylenetriamine pentaacetic acid (CaDTPA; Pentetate calcium trisodium injection) Zinc-diethylenetriamine pentaacetic acid (ZnDTPA; Pentetate zinc trisodium injection)

Pois on /Drug /Toxi n   Internal contamination with transuranium elements: americium, curium, plutonium

Potassium Iodide, KI ® tablets (Iostat,    ® Thyro-Block, ® Thyrosafe ) ® KI liquid (Thyroshield , ® SSKI )

Prevents thyroid uptake of radioactive iodine (I-131)

Prussian blue, ferric hexacyanoferrate (Radiogardase®)

Radioactive cesium (Cs-137), radioactive thallium (Tl-201), and nonradioactive thallium

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Suggested Minimum Stock Quantity Quantity determined by institution. Supplied as 200 mg/ML, 5 mL ampules for IV or inhalation administration. The product is sponsored through Hameln Pharmaceuticals, GmbH, of Hameln, Germany. Distributed in the United States by Akorn, Inc.

Quantity determined by institution.  Available in 130 mg and 65 mg tablets, and PO solutions: 65 mg/mL (30 mL bottle) and 1 g/mL (30 mL and 240 mL bottle).

2008 Illinois Poison Center. Updated September 2008

None recommended at the present time.  Available in bottles of 30 capsules (500 mg/capsule). The product is manufactured by Haupt Pharma Berlin GmbH for distribution by HEYL Chemisch-pharmazeutische Chemisch-pharmazeutis che Fabrik GmbH & Co. KG, Berlin, Germany, and is available in the U.S. from Heyltex Corporation.

Rationale/Comments Ca-DTPA and Zn-DTPA are available through the Strategic National Stockpile (SNS) and REAC/TS, Oak Ridge, Tennessee.

KI tablets and oral solution are non-prescription. The Illinois Department of Nuclear Safety makes KI tablets available to healthcare facilities and the general public located near nuclear reactors.

Prussian Blue is also available through the Strategic National Stockpile (SNS) and REAC/TS, Oak Ridge, Tennessee.

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